Report on In Plant Training In Beximco Pharmaceuticals (Part-4) - Assignment Point
Report on In Plant Training In Beximco Pharmaceuticals (Part-4)
Subject: Entrepreneurship Development, Management | Topics: ,

Liquid Dosage Formulation

LCO Department of Beximco Pharmaceuticals Limited produces about 84 products of various dosages form including

(i)         Syrup (example: Napa, Aristoplex)

(ii)       Suspension (example: Lactameal, Flatameal DS)

(iii)     Nasal spray (example: Decomit)

(iv)     Drops (Example: Deflux Ped. Drop)

(v)       Suppositories (example: Napa, Ultrafen)

(vi)     Cream, Ointment, Gel (example: Neostin cream, Anustat ointment, Ultrafen gel)

LCO Department of BPL consist following 6 lines:

i.Line-1: Syrup, Suspension.

ii.Line-2: Antacid preparation

iii. Line-3: Small volume oral liquid preparations

iv.Line-4: Cream, Ointment

v.Line-5: Oral liquid suppository facility (OLSF), Syrup

vi. Line-6: Suppository

Syrup Manufacturing

Capture

Suppository Manufacturing

Capture

Ointment Manufacturing

Capture

Observed Manufactured Products

Product Category

Product Name

Operations Observed

SyrupTofenFilling, sealing & packing
SyrupNapa (60ml & paediatric drop)Manufacturing
SuspensionFlatameal DSFilling, sealing & packing
CreamNeostinManufacturing

Machine list of Liquid, Cream, Ointment and Suppository Department,

Line #01

SL

No.

Machine Name

Model &

Sr. No.

Manufacturer

Capacity

Use

1.Manufacturing vesselMV- 5000Tanners fabricated ltd, Australia.5000LManufacturing of liquid syrup & suspension.
2.Storage vessel & agitatorSV – 5000Tanners fabricated ltd, Australia5000LStorage of liquid
3.Inline mixer & Transfer pumpIM  – 600Silverson, England400L, 400psiOnline mixing & transfer of liquid syp & sus.
4.Filtering M/C milliporeFM-MPMillipore, USA5000L/hrFiltering of fluid
5.Vessel with Fluid agitatorFA – 942Lab. Equipment, India1000LStirring & mixing.

Line #02

SL

No

Machine Name

Model & Sr. No.

Manufacturer

Capacity

Use

1.Manufacturing vesselMV- 3000Tanners fabricated ltd, Australia.3000LManufacturing of liquid suspension
2.Storage vessel & agitatorSV – 3000Tanners fabricated ltd, Australia.3000LStorage of liquid suspension
3.Inline mixerIM  – 440Silverson, England600L ,  440psiOnline mixing & transfer of liquid

Line #03

SL

No

Machine Name

Model & Sr. No.

Manufacturer

Capacity

Use

1.Fluid agitatorFA – 944Lab. Equipment, India250 rpmStirring & mixing
2.Liquid mixer SilversonLM – SILSilverson, England450LLiquid  & cream homogenizer
3.Liquid transfer pumpLTP- 40Frymamachinen, Switzerland1000L/hTransfer of liquid
4.Filtering M/C SartoriousFA- SASartorious, Germany1000L/hFilter
5.Seitz Kettle Germany200 L/hManufacturing vessele
6.Vertical Ultrasonic cleaning machine China50-200 pcs/minBottle washing
7.FAR Infrared sterilizing and drying tunnel Changsha, China50-300 pcs/minBottle drying
8.Filling and Plugging machine Changsha, China50-100 pcs/minBottle filling and sealing

Line #04

SL

No

Machine Name

Model & Sr. No.

Manufacturer

Capacity

Use

1.Planetary mixerPLM-100Gansons, India50LMixing
2.Colloid  millCOLL-MProbst & glass, Germany250 kg/hrMixing and blending of materials
3. General purpose mixing machineGP-MMSeitz, Germany100LMixing

Line #05

SL

No

Machine Name

Model & Sr. No.

Manufacturer

Capacity

Use

1.Manufacturing vessel   –Tanners fabricated ltd, Australia.5000LManufacturing of liquid syrup & suspension
2.Storage vessel & agitator   –Tanners fabricated ltd, Australia5000LStorage of liquid
3.Filtering Machine millipore   –Millipore, USA5000L/hrFiltering of fluid
4.Auto Filling , Sealing, Bottle washing &  Labeling machine

 

   –Pharmalab, India6000Bot./hrWashing, Filling, Sealing&  Labeling of Bottles

Line #06 (Suppository)

SL

No

Machine Name

Model  No.

Manufacturer

Capacity

Use

1.SarongD-402Italy5000 suppo/hrFilling & Sealing of  Suppository
2.Manufacturing vessel   –Thailand100LManufacturing

Unit: Filling

Line #01

SL

No

Machine Name

Model  No.

Manufacturer

Capacity

Use

1.Automatic liquid filling M/C(ATOMAT)   –S.S Industries,India85-100b/m1.Bottle washing & drying

2. Liquid filling & cap sealing

3.Labelling & printing

Line #02

SL

No

Machine Name

Model & Sr. No.

Manufacturer

Capacity

Use

1.Automatic liquid filling M/C(ATOMAT)Monobiock FillerS.S Industries, India3000b/hLiquid filling
2.

 

Cap sealing machine

 

CS-V46Vaw, Germany28-32b/mCap sealing
3.Self adhesive labeling machine   –Clear pack, Singapore110b/mBottle labeling

Line #03

SL

No

Machine Name

Model & Sr. No.

Manufacturer

Capacity

Use

1.Liquid filling machineLFM-L1Local30-35b/mLiquid filling
2.Cap sealing machine

 

CS-V47Vaw, Germany28-32b/mCap sealing
3.Laminar Air Flow Cabinet   –      –        –To control bacteria in the filling area

Line #04

SL

No

Machine Name

Model & Sr. No.

Manufacturer

Capacity

Use

1.Automatic tube filling & sealing machine

 

830920Greatide, Taiwan25-55 tube/minCream & Ointment filling & sealing

Unit: Overprinting

SL

No

Machine Name

Model & Sr. No.

Manufacturer

Capacity

Use

1.Semi-automatic over printing MachineHAPA-LProntop hot hapa, Switzerland4000p/hPrinting label
2.Automatic over printing MachineKK-610Jiangcozzer, Taiwan4000p/hPrinting label & carton
3.Semi-automatic printerSAP-LLocal1500p/hPrinting label & carton
4.Automatic over printing machineKK-560Taiwan4000p/hPrinting carton
5.

 

Automatic over printing machineKK-550Taiwan4000p/hPrinting carton

Bottle washing area

SL

No

Machine Name

Model & Sr. No.

Manufacturer

Capacity

Use

1.Rotary bottle washerDR W3Pharmalab, India5000b/hBottle washing
2.Rotary bottle dryerSTDGansons, India2500b/hBottle drying
3.Hot air dryer  –Heraeus450b/loadDrying of (mainly pasteurization) bottle
4.Hot air dryerHAD78Gansons, India830b/loadDrying of (mainly pasteurization) bottle
5.Sterilization oven MemmbrtSO-MEMMEMBRT, Germany800-840 b/loadSterilization &drying
6.Rotary bottle washer  –Pharmalab, India5000b/hBottle washing

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