Human Interactome

The human interactome is the set of protein-protein interactions (the interactome) of which occur in human cells. The sequencing of reference genomes, in particular the Human Genome Task, has revolutionized human genetics, molecular chemistry and biology, and clinical medicine. Genome-wide association analyze results have triggered the association of genes with many Mendelian disorders, and over one hundred and 40,000 germline mutations have been associated with one or more genetic disease.