The aim of this lecture is to present on Tissue and Organ Transplantation. Today it is possible to transplant many different organs and tissues including. Most common transplantation is blood transfusion and Bone Marrow transplantation. Organs : Heart, kidneys, pancrease, lungs, liver and intestines. Tissues : include bones, corneas, skin, heart values, veins, cartilage and other connective tissues. Here also briefly present on Heart Transplantation and Lung Transplantation.