Basic objective of this lecture is to present on Human Health and Disease. Health is the state of complete physical, mental and social well-being’. To sustain a healthy lifestyle person needs: a balanced and varied diet; take exercise; proper shelter and enough sleep. In humans it is the ability of individuals or communities to adapt and self-manage when facing physical, mental or social challenges. Disease is a disorder or malfunction of the mind or body, which leads to a departure from good health. Can be a disorder of a specific tissue or organ due to a single cause. E.g. malaria.