Principle objective of this article is to explain Significance of Clinical Trials. Clinical trial is usually a research study done to ascertain if a new treatment or therapy is secure and efficient. The existing treatments for most medical conditions might not be effective for everyone. These trials can assist determine whether new treatments are safer or more effective than those currently used. The treatments chosen show potential for being better than recent treatments, although, sometimes are certainly not as effective. Most medical treatments which might be widely available have been tested in clinical trials in the past.