Bangladesh is a storehouse of numerous kinds of plants and most of them have medicinal value. Polygonum plebejum is one of the important plants of Polygonaceae family. The natives take this plant as leafy vegetable and used for the remedy of different diseases.
For the present work, the plant was collected from low land area of Mohammadpur. The collected plant was cut into small pieces, dried in an oven at 40oC and powdered mechanically; this powdered sample was extracted with petroleumether and followed by ethylacetate exhaustively. The extracts were concentrated separated to a dry mass. The dry mass (8.683 g) of the ethylacetate extract was subjected to VLC for separation of different compounds.
Phytochemical screening of this plant was carried out from its aqueous extract and taking the powdered specimens using standard procedures. This screening indicated the presence of Alkaloid, Tannin, Saponin, Steroid, Terpenoid, and Cardiac glycoside and quantitative estimation of Alkaloid, Flavonoids, Saponin were carried and their percentage were found to be 0.8, 14.06, 8.5 respectively.
The fractions obtained from ethylacetate extract by VLC using different ratio of elutions were marked as F1, F2, F3, F4, F5, F6, F7, and F8. These fractions were analyzed separately from the fraction F2 and F5 yielded single compounds. Fraction F2 gave single compound (0.892 mg). Its IR was recorded and due to its small amount, it was not further studied.
The fraction F6 was concentrated to a small volume in vacuum and left undisturbed at room temperature for several days when a solid (4.106 mg) was appeared. It was again dissolved in methanol and its TLC studies showed that it was a single compound with Rf value (0.5) having light yellow crystal.
The fraction F3 was concentrated to a small volume in vacuum and left undisturbed at room temperature for several days when a solid (6 mg) was appeared. It was again dissolved in methanol and its TLC studies showed that it was mixture compound with light yellow oily substances. Due to lack of time, further study was not possible. Only IR spectrum analysis was carried out.
The fraction F7 was concentrated to a small volume in vacuum and left undisturbed at room temperature for several days when greenish gummy material was appeared. It was again dissolved in methanol and its TLC studies showed that it was mixture compound with gummy substances. Due to lack of time, further study was not possible. Only IR spectrum analysis was carried out.
Attempt was taken to characterize this Compound (SPPA1) by M.P., IR (Figure- 2.4), 1H-NMR (Figure-2.5 ) & 13C-NMR (Figure-2.9 ) spectral data and it was tentatively suggested to be 2,6-dihydroxy-3-acetyl-4-methyl-cyclohex-4-enyl isostearate.
Fatty acids (free fatty acids and bound fatty acids) of the Polygonum plebejum were analyzed. The compositional analysis of petroleumether extract of Polygonum plebejum by GC revealed that the bound fatty acid portion of this plant was rich in unsaturated fatty acids (such as Stearic acid, Oleic acid, Myristic acid, Lauric acid and Lignoceric acid). No free fatty acid was identified, may due to its trace amount.
The percentages of ash and moisture in this plant of Polygonum plebejum were determined by standard method and they were found to be 14.89 % and 14.04 % respectively in dry powder basis.
The anti-microbial tests of petoleumether extract, ethylacetate extract, methanol extract and water extract of Polygonum plebejum were carried out against 4-types of bacteria by disc diffusion method. All extracts except water extract were found to be inactive against these test organisms.
Fatty acids and ash analysis of Polygonum plebejum indicated that this plant may taken a diet as vegetable. Its anti-microbacterial analysis indicated its medicinal importance. It’s further phytochemical analysis studies can lead to isolation of some new compounds, which may have therapeutic value. On the basis of findings, it can be concluded that this plant Polygonum plebejum has importance as a diet as well as its medicinal value.
Plants play an important role1 in our life. Plants2 have been providing the human beings with the basic necessities of life; that is food, fuel and shelter, from the very beginning of their existence, and for their continued living.
Plants and man2 are inseparable. Because plants not only provide man the basic needs of life but also the life sustaining oxygen gas. Since man encountered diseases, got injured and wounded, faced decay of health. So, to live on earth the early man had to think about disease and its treatment at the very dawn of human intellect. And plants were the first natural substances that man could think of its use as a means of treatment of diseases. From ancient time to modern age, the human race has successfully used plants and plant products as effective therapeutic tools fighting against diseases and various other health hazards.
Again plants produce other substances by metabolic processes, such as glycosides, steroids, terpenoids, alkaloids, resins, essential oils, tannins, flavonoids, pigments etc. These are usually called secondary metabolites. Some of the compounds are harmful to animal life but some of them have proved to be tremendously effective in therapeutic doses for successful remedies for a number of diseases. Many chemical compounds of diversified nature from plants often played an important role to give a new direction for laboratory synthesis of many new classes of drug molecules.
Related Chemistry Paper:
Popular Chemistry Paper:
Objective: The main purpose of the project is to maintain fluid in a desire level to any control system. PLC is used in this project as an Automation tool to reduce manual operation and get better accuracy. Introduction: In the past, humans were the main methods for controlling a system. More rec.....
Introduction: Our country has many types of natural resources. Natural Gas is one of the most important of natural resources. Our country has huge natural gas. Bangladesh natural gas production began in 1960 from the Chattak Filed. There is much uncertainty and debate about the level of natural g.....
Atomic Absorption spectroscopy is one of the excellent analytical instruments for the analysis of the chemical composition of samples. Walsh was first introducing the instrument as a general purpose, now it is very popular analytical technique to determination of different elements. It is based o.....
Basic objective of this lecture is to presentation on Pentose Phosphate Pathway. Other names of Pentose Phosphate Pathway is Phosphogluconate Pathway and Hexose Monophosphate Shunt. Here briefly explain the linear part of the pathway carries out oxidation and decarboxylation of the 6-C sugar gl.....
INTRODUCTION Pulp is the fibrous cellulosic material used in the production of paper. Wood is the principal raw material for the production of pulp; but bamboo, cotton, linen, rags, straw, bagasse, etc are also used. Chemical pulp production is the cooking of the wood raw material with chemicals......