Biology

Osteocyte Definition Osteocyte is a cell characteristic of mature bone tissue. It is derived from osteoblasts and embedded in the calcified matrix of bone. Osteocytes…

Osteoclast Definition Osteoclast is a specialized bone cell that absorbs bone, allowing for the deposition of new bone and maintenance of bone strength. The osteoclast…

Androgen Receptor Definition Androgen receptor is a key mediator of androgen function within normal and malignant prostate cells. It is mainly expressed in androgen target…

Transcription Factor Definition Transcription factors (TFs) are proteins that regulate the transcription of genes—that is, their copying into RNA, on the way to making a…

Heat Shock Protein Definition Heat shock protein (HSP) is an intracellular protein that increases in concentration during metabolic stress, such as exposure to heat. HsPs…

Steroid Hormone Receptor Definition Steroid hormone receptor includes 48 receptors for the gonadal and adrenal steroids, nonsteroidal ligands such as thyroid hormones, vitamin D, retinoic…

Glucocorticoid Receptor Definition Glucocorticoid Receptor (GR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1), which is mediates actions of glucocorticoids (GCs)…

Glucocorticoid Definition Glucocorticoid is any of a group of anti-inflammatory steroidlike compounds, such as hydrocortisone, that are produced by the adrenal cortex, are involved in…

Cortisol Definition Cortisol is the principal steroid hormone produced by the adrenal cortex. It regulates carbohydrate metabolism and the immune system and maintains blood pressure.…

Adrenal Gland Definition Adrenal gland is a small gland located on top of the kidney. The outer portion, or cortex, secretes steroid hormones (corticosteroids). The…

Choroid Plexus Definition Choroid plexus is a small organ located inside the nervous system, more precisely in the brain in proximity to the ventricles. The…

Lateral Ventricles Definition Lateral ventricles are the largest in the series of four interconnecting fluid-filled cavities within the brain. These cavities and theirs interconnecting channels,…