Topic:Presentation on Klinefelter syndrome
1. Klinefelter syndrome:
Klinefelter syndrome is a genetic disorder that affects males. Most males have one X and one Y sex chromosome. But when a boy is born with one or more extra X chromosomes, Klinefelter syndrome occurs.
2. Genetic causes:
Klinefelter’s syndrome is caused by an extra X chromosome and affects only males. An infant with Klinefelter’s Syndrome appears normal at birth, but the defect usually becomes apparent in puberty when secondary sexual characteristics fail to develop, and testicular changes occur that eventually result in infertility in the majority of those affected.
But it can also occur when the genetic material in the sperm splits unevenly.
3. Signs and syndromes:
- Reduced facial and body hair.
- Small penis
- Sexual dysfunction
- Enlarged breast tissue
- Abnormal body proportions (long legs, short trunk)
- Learning disabilities,
4. Treatment for Klinefelter syndrome :
- Testosterone replacement therapy
- Breast tissue removal
- Speech and physical therapy
- Fertility treatment
- Psychological counseling
5. Can Klinefelter syndrome be inherited?
This condition is not inherited; it usually occurs as a random event during the formation of reproductive cells (eggs and sperm). An error in cell division called non-disjunction results in a reproductive cell with an abnormal number of chromosomes.
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