Chemistry

Lecture on Glycogen Metabolism

Lecture on Glycogen Metabolism

General objective of this lecture is to presentation on Glycogen Metabolism, in perspective of Biochemistry of Metabolism. Glycogen is a polymer of glucose residues linked by alfa glycosidic bonds, here is find out Glycogen chains and branches are longer than shown and Glucose is stored as glycogen predominantly in liver and muscle cells. Here also briefly discuss on Pyridoxal phosphate, Pyridoxal phosphate (PLP) is held with the active site by a Schiff base linkage, formed by result of the aldehyde of PLP using the e-amino group of a lysine residue. In contrast to its role inside other enzymes, the phosphate of PLP is involved in acid/base catalysis by Phosphorylase. Finally explain Glycogen Phosphorylase: a homodimeric enzyme, subject to allosteric control.